Cholesterol-Lowering Bile Acid Blockers Increase Risk For Mental Decline

Cholesterol-Lowering Bile Acid Blockers Increase Risk For Mental Decline: For the first time medical investigators have made a link between irregularities in the breakdown of cholesterol into bile and the development of dementia (forgetfulness, thinking, having an “adult moment).” For over 40 years physicians have prescribed a class of cholesterol-lowering drugs that bind to bile, bile being composed of cholesterol.  Drugs that attempt to lower circulating levels of cholesterol are now associated with beta amyloid plaque in the brain. These findings were primarily observed in males.  The pharmacological practice of lowering bile levels with the use of bile-binding drugs (bile acid sequestrants) may impair signaling in the brain which … Continue reading →